White Sox vs. Guardians odds, prediction: MLB picks for Wednesday, April 10

White Sox vs. Guardians odds, prediction: MLB picks for Wednesday, April 10

After picking up just their second pick of the season, the Chicago White Sox look to grab the series victory over the Cleveland Guardians Wednesday night.

Let’s take a closer look at the rubber match at Cleveland’s Progressive Field and provide a best bet for the game.

White Sox vs. Guardians odds

Run line: White Sox: +1.5 (-105), Guardians -1.5 (-114)
Moneyline: White Sox +200, Guardians -245
Total: o7.5 (-108), u7.5 (-112)

Odds via FanDuel

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White Sox vs. Guardians analysis: Prediction

The White Sox (2-9) used a five-run first inning to beat the Guardians on Tuesday night, 7-5. Cleveland rallied back to tie the game up at 5-5 before the Sox plated a pair of eighth-inning runs to take the lead for good and cash as +210 underdogs.

In Wednesday night’s finale, right-hander Erick Fedde makes his third start of the young season for Chicago after two impressive outings. The former Washington Nationals hurler has allowed three earned runs in nearly 10 innings of work, although the Sox lost each of those games by one run apiece.

Tanner Bibee, who counters for Cleveland on the mound, owns a 2-0 record with a 3.86 ERA. Bibee struck out nine batters in 5.1 innings in a 4-2 victory at Minnesota in his last outing. He’ll be making his first home start of the season.

The Guardians won eight of Bibee’s 12 home outings in 2023, although he did not face the White Sox at Progressive Field. Bibee made one start against Chicago in 2023, giving up three runs and two homers in a 6-3 Cleveland victory.

White Sox vs. Guardians pick

The two American League Central rivals combined for 10 runs Tuesday night in the first five innings, but you should expect that number to drop in the series finale.

Fedde has seen the under cash in each of his first two outings in the first five innings with three and two combined runs scored, respectively.

The Sox, on the other hand, have been held to one or fewer runs in the first five innings in eight of 11 games this season.

Pick: Under 4.5 runs, first five innings (-135, DraftKings)

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